Incidence of laryngeal cancer and exposure to acid mists.
Steenland-K; Schnorr-T; Beaumont-J; Halperin-W; Bloom-T
Br J Ind Med 1988 Nov; 45(11):766-776
The relation between exposure to acid mists and the incidence of laryngeal cancer was studied using a cohort of 879 men exposed to acid mists during pickling operations in three steel mills. The men had worked for at least 6 months in a pickling department of a steel mill, and the average duration of exposure was 9.5 years. A total of 62 percent of the cohort was exposed only to sulfuric-acid (7664939) mists, and 22 percent was exposed to a mixture of sulfuric- acid and other acid mists. Sixteen percent of the cohort was exposed only to acid mists other than sulfuric-acid. Sulfuric-acid concentration ranges estimated from personal samplers were 0.07 to hooker, and 0.15 to 0.29mg/m3 for craneman. Area samples ranged from 0 at the crane stairs to 1.20mg/m3 at the cold strip mill. The men or next of kin of decedents were contacted by mailed questionnaire followed by telephone interviews for nonrespondents. Nine workers were diagnosed as having laryngeal cancer relative to an expected rate of 3.92 in the general population (adjusted for excess smoking), yielding a standardized incidence ratio for laryngeal cancer in the cohort of 2.30. The authors conclude that workers exposed to acid mists have an increased risk of laryngeal cancer.
NIOSH-Author; Cancer-rates; Occupational-exposure; Air-contamination; Steel-industry; Pulmonary-system-disorders; Morbidity-rates; Epidemiology; Acid-mists; Larynx-cancer
British Journal of Industrial Medicine