The relative importance of pesticide poisonings as health hazards in Iowa agriculture.
NIOSH 1976 May; :1-11
Occupational health hazards on Iowa farms were discussed, and the importance of pesticide poisoning was evaluated. Pesticide poisoning was considered to rank fourth among hazards in Iowa agricultural practice. Skin irritations and sensitizations were the most common problems arising from pesticide usage. Most of the poisoning cases reported were those arising from accidental ingestion of pesticides stored around the home, or suicide attempts. There appeared to be no need for a large scale safety monitoring program directed either at farmers or farm laborers in the Iowa area or for exhaustive studies of field reentry hazards. Data obtained in a study of the use of urinary metabolites of methyl-parathion (298000) and ethyl-parathion (56382) to measure the absorption of these pesticides to farm workers were presented. In this study four human subjects ingested 2 dose levels of either methyl-parathion or ethyl-parathion for 5 consecutive days. The doses used were not sufficient to depress blood cholinesterase activities nor was either compound detectable in plasma samples taken 20 minutes to 2 hours following ingestion. Urinary metabolites were found which were quite specifically related to absorption of the parathions.
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