Mortality Analyses Using United Auto Workers' Cohorts.
Park R; Silverstein M; Maizlish N; Mirer F
Evidence was presented to supports the legitimate standing of proportional mortality design studies as a valuable means of investigating occupational disease mortality. In an Illinois based study of grey iron foundries, personnel records were used to define exposure groups and a significant excess of nonmalignant respiratory disease consisting largely of emphysema was noted among workers in the finishing department where the work consisted mainly of chipping, grinding, and cleaning. Exposure to silica (7631869) was suspected. Significant excesses in lung cancer were also found. In a ball bearing facility, a clear association was found between working in grinding categories 15 years prior to death and stomach cancer. Yet another study involved the deaths of 200 men and 75 women at an electronics fabrication facility in Michigan where aircraft and missile instruments and control systems were manufactured. Exposures at this facility included halogenated solvents, epoxy resins, and a variety of other polymerizing systems, cutting fluids, and soldering fumes. Excesses of pancreatic cancer were identified in both men and women. For women there were also excesses of colon and ovarian cancer. Findings from a study of auto repair workers suggested that a negative trend existed for nonmalignant respiratory disease and also indicated a lack of dependence on age at death in relation to the incidence of cancer of the esophagus.
Mortality-rates; Mortality-surveys; Epidemiology; Foundry-workers; Pulmonary-system-disorders; Lung-disorders; Organic-solvents; Solderers; Gastrointestinal-system-disorders; Reproductive-system-disorders; Automobile-repair-shops;
Asthma and Chronic Obstructive Pulmonary Disease; Disease and Injury; Pulmonary-system-disorders; Fertility and Pregnancy Abnormalities; Reproductive-system-disorders;
Proceedings of the Fourth NCI/EPA/NIOSH Collaborative Workshop: Progress on Joint Environmental and Occupational Cancer Studies, April 22-23, 1986, Rockville, Maryland, NIH Publication No. 88-2960