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Health hazard evaluation determination report no. HHE-78-6-503, Cumberland Outpatient Department of Beth Israel Hospital, Brooklyn, New York.
Messite J; Fannick NL
Cincinnati, OH: U.S. Department of Health, Education, and Welfare, Public Health Service, Centers for Disease Control, National Institute for Occupational Safety and Health, HHE 78-6-503, 1978 Jul; :1-3
In response to a request from a representative of the nursing staff, an investigation was made of possible methadone (76993) exposures at the Cumberland Outpatient Department of Beth Israel Hospital, Brooklyn, New York, a methadone dispensing clinic. The distribution room measured 12 feet in all dimensions and was enclosed on three sides. Methadone had previously been received in prepackaged doses, but more recently the nurses had to count the contents of each 100 count bottle of methadone-hydrochloride (1095905) and separate tablets or diskets into individual doses. A small amount of pink orange dust, due to chipping and breakage of pills, was noted during the on site visit, on the countertops where the drug was counted. Nurses involved in dispensing the medication reported intermittent sleepiness, itching of the face, nose, and eyes, and dryness of skin on the hands and face. Urine studies indicated no detectable methadone or methadone metabolites at a limit of 1 microgram per milliliter. The authors conclude that there is no evidence of methadone absorption; however, they recommend that skin contact with the tablets and diskets be kept to a minimum by use of instruments for moving the pills on the counting tray, frequent clean up of dust, and periodic hand washing.
NIOSH-Author; NIOSH-Health-Hazard-Evaluation; HHE-78-6-503; Region-2; Hazard-Unconfirmed; Health-care-personnel; Metabolic-study; Skin-exposure; Skin-absorption; Urinalysis; Clinical-symptoms; Narcotics; Drug-therapy; Author Keywords: methadone; methadone dispensing clinic; dose counting
Field Studies; Health Hazard Evaluation
NTIS Accession No.
National Institute for Occupational Safety and Health
Page last reviewed: September 2, 2020
Content source: National Institute for Occupational Safety and Health Education and Information Division