Some of the emerging issues and research that pertain to women in the workplace are briefly discussed. Over half of the female population of working age in the United States is employed and health hazards confronting women are expected to increase. Most research on job stress has pertained mainly to men and little is known about the impact of job stressors on women and their families. Women in the workplace suffer many psychosocial stresses due to the fact that whether blue or white collar, women usually have a low status, low pay, repetitive, boring, and physically restraining jobs with high production goals. Sexual harassment, sex role blurring, sex discrimination, and coronary heart disease are all significantly correlated with the stressors on women at work. The additional role of mother and care giver may further add to stress in working women. Occupational health nurses provide a wide variety of health services to organizations, but the diversity of the working woman intensifies the occupational health nursing (OHN) challenge. The author concludes that the occupational health nurse must become a vital link between the employee and health at the worksite and serve as a sentinel for the early detection of problems.