NIOSHTIC-2 Publications Search

Health studies of miners and millers exposed to talc.

Authors
Gamble JF; Greife A
Source
Health issues related to metal and nonmetallic mining. Wagner WL, Rom WN, Merchant JA, eds. Boston, MA: Butterworth, 1983 Jan; :277-302
Link
NIOSHTIC No.
00170700
Abstract
Occupational lung disease was studied in workers who mined and milled talc (14807966) in New York, Montana, Texas, and North Carolina. Occupational exposure to talc has been associated with silicosis and interstitial fibrosis. In the population studied, personal air samples were collected to determine time weighted average exposures to respirable dust, free silica, and mineral particulate. Cumulative exposures were calculated on the basis of job classification. Chest radiographs and pulmonary function tests were evaluated for all workers. The entire study population was classified according to age, height, sex, smoking habits, weight, region of employment, and presence or absence of cough, phlegm, dyspnea, and pleural thickening. Analysis of intraregion dose response relations showed no consistent or strong association of exposure with respiratory symptoms and pulmonary function. A statistically significant association of bilateral pleural thickening with exposure was found, and was dose related in all regions except Texas. Sex, age, height, and smoking were, in general, significant predictors of pulmonary function. The authors conclude that their findings support the hypothesis that talc is a causative agent of pleural thickening. However, they state, the relationship between pleural thickening and mortality is unknown.
Keywords
Workplace-studies; Morbidity-rates; Respirable-dust; Occupational-respiratory-disease; Mine-workers; Air-sampling; Talc-dust; Pleural-cavity; Occupational-exposure; Pulmonary-system-disorders
CAS No.
14807-96-6
Publication Date
19830101
Document Type
Conference/Symposia Proceedings
Editors
Wagner WL; Rom WN; Merchant JA
Fiscal Year
1983
ISBN No.
9780250406104
NIOSH Division
DRDS
Source Name
Health issues related to metal and nonmetallic mining. Wagner WL, Rom WN, Merchant JA, eds. Boston, MA: Butterworth, 1983 Jan; . Proceedings of the Fourth Annual RMCOEH Occupational and Environmental Health Conference, April 7-9, 1982, Park City, Utah, sponsored by the Rocky Mountain Center for Occupational and Environmental Health
State
WV; MT; NY; NC; TX; MA; UT
Page last reviewed: April 12, 2019
Content source: National Institute for Occupational Safety and Health Education and Information Division