Cincinnati, OH: U.S. Department of Health and Human Services, Public Health Service, Centers for Disease Control, National Institute for Occupational Safety and Health, IWS 117-16, 1986 Jun; :1-52
Occupational exposure to polychlorinated dibenzo-p-dioxins, and in particular 2,3,7,8-tetrachlorodibenzo-p-dioxin (1746016) (2,3,7,8- TCDD) and hexachlorodibenzo-p-dioxin (HxCDD) isomers, were investigated and compiled in the Dioxin Registry. The Diamond Alkali Company's facility, located in Newark, New Jersey, was one of 14 sites included in the Dioxin Registry. From 1951 to 1969, sodium- 2,4,5-trichlorophenate (136323), and 2,4,5-trichlorophenoxyacetic- acid (93765), esters, and amines were produced at this site. All were contaminated with 2,3,7,8-TCDD. Operators involved in the production of sodium-2,4,5-trichlorophenate had potential exposures to 2,3,7,8-TCDD while operating the autoclave reactor, collecting samples from the reactor, operating the dilution/filtration product recovery system, and operating the anisole still and product recovery system. The 2,3,7,8-TCDD concentrations associated with the autoclave reactor, dilution filtration, and anisole still were about 20, 10, and 70 micrograms/gram (microg/g), respectively. Reslurry tank and acidification tank operators preparing 2,4,5- trichlorophenoxyacetic-acid had potential 2,3,7,8-TCDD exposures of 20microg/g. Prior to 1967, the production and operator helpers performing formulations and aminizations were potentially exposed to 20microg/g 2,3,7,8-TCDD contamination. This level dropped after 1967 to 1 and 0.5microg/g, respectively, for each process.