Skip directly to search Skip directly to A to Z list Skip directly to page options Skip directly to site content

NIOSHTIC-2 Publications Search

Search Results

Histoplasmosis.

Authors
Band-JD
Source
Occupational respiratory diseases. Merchant JA, Bochlecke BA, Taylor G, eds. Morgantown, WV: U.S. Department of Health and Human Services, Public Health Service, Centers for Disease Control, National Institute for Occupational Safety and Health, DHHS (NIOSH) Publication No. 86-102, 1986 Sep; :699-702
NIOSHTIC No.
00170173
Abstract
Histoplasmosis is reviewed with regard to etiology, epidemiology, pathology, diagnostic criteria, methods of prevention, and research needs. Histoplasmosis is defined as a systemic fungal infection caused by the soil fungus Histoplasma-capsulatum. The organism is most heavily concentrated in the central United States, and more than 90 percent of the residents of the Ohio, Mississippi, and Missouri river valleys were shown to have evidence of being infected. Persons having close contact with the soil, particularly soil enriched with avian and bat feces, have been identified as being at high risk. Occupations at risk include farmers, bird handlers, construction workers, landscapers, earth movers, and workers involved in the cleaning or dismantling of contaminated buildings. The clinical manifestation of the primary acute disease is minimal in 95 percent of persons infected. Progressive disseminated histoplasmosis ia rare except in individuals at the extremes of age or immunologically compromised persons. Chronic progressive pulmonary histoplasmosis ia uncommon unless significant cavitation is evident. The chronic cavitary disease, left untreated, results in progressive pulmonary disability and death in 50 percent of affected persons within 5 years. Progressive pulmonary histoplasmosis occasionally results from excessive fibrosis of the lungs and lymph nodes.
Keywords
Environmental-exposure; Fungal-diseases; Biological-material; Plants; Fungal-infections; Respiratory-infections; Construction-workers; Agricultural-workers; Animal-husbandry-workers
Publication Date
19860901
Document Type
Chapter
Editors
Merchant-JA; Bochlecke-BA; Taylor-G
Fiscal Year
1986
NTIS Accession No.
NTIS Price
NIOSH Division
DRDS
Source Name
Occupational respiratory diseases
State
MS; MO; OH
TOP