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NIOSH Testimony on Certain Carcinogens by M. M. Key, September 14, 1973.
NIOSH 1973 Sep:164 pages
This testimony was divided into two major parts. In the first, the speaker reported on six NIOSH supported studies regarding the occupational dangers to coke oven workers including a seven fold increase in the risk of developing kidney cancer. The second part of the testimony presented Hazard Reviews and called for the inclusion of several chemical carcinogens in the standard. These other chemicals included: 2-acetylaminofluorene (53963), 4- aminodiphenyl (92671), benzidine (92875), bis(chloromethyl)ether (542881), 3,3'-dichlorobenzidine (91941), 4-dimethylaminoazobenzene (60117), ethylenimine (151564), chloromethyl-methyl-ether (107302), alpha-naphthylamine (134327), beta-naphthylamine (91598), 4- nitrobiphenyl (92933), N-nitrosodimethylamine (62759), and beta- propiolactone (57578). The reports on some of these substances contained epidemiological evidence of increased cancer risks for individuals exposed to these substances in an occupational setting. Others of the reports were included on the basis of animal studies which supported the strong probability that these chemicals were carcinogens for humans as well. No evidence existed at this time to indicate that any of these substances was not carcinogenic to man and therefore strict measures regulating the exposure to these substances in the workplace are recommended.
NIOSH-Author; NIOSH-Testimony; Key-M-M; Carcinogenesis; Cancer-rates; Risk-analysis; Coke-oven-emissions; Coke-oven-workers; Chlorinated-hydrocarbons; Aromatic-hydrocarbons; Azo-compounds; Nitroso-compounds; Amines; Lactones;
53-96-3; 92-67-1; 92-87-5; 542-88-1; 91-94-1; 60-11-7; 151-56-4; 107-30-2; 134-32-7; 91-59-8; 92-93-3; 62-75-9; 57-57-8;
NTIS Accession No.
NIOSH, 164 pages, 412 references
Page last reviewed: April 12, 2019
Content source: National Institute for Occupational Safety and Health Education and Information Division