Sampling and analysis of 2,6 di-t-butyl-p-cresol (DBPC).
Am Ind Hyg Assoc J 1978 Jan; 39(1):78-82
A method for determining 2,6-di-t-butyl-p-cresol (128370) (DBPC) exposure was developed. Initial attempts at field sampling for DBPC using a silver membrane filter backed with a charcoal tube proved inadequate. Silica gel tubes were found to provide an efficient sampling medium from which DBPC could be recovered quantitatively. The desorption efficiency with carbon-disulfide was only 50 percent; however, this was improved dramatically by addition of 5 percent methanol to the carbon-disulfide. With a minimum desorption time of 60 minutes, recoveries of 90 percent or better were obtained for absorbed concentrations of 0.05 and 0.2 milligrams per tube. Flame ionization gas chromatography and an SE-30 column provided the fastest and most reproducible analysis. The authors conclude that DBPC can be sampled in the industrial atmosphere using silica gel tubes. The authors recommend a total sampling volume of 10 liters in an atmosphere containing 5mg/m3, and the desorption and analysis of the glass fiber plug, used to hold the silica gel in place, along with the silica gel for total quantitation of both DBPC dust and vapor.
NIOSH-Author; Toluenes; Air-samples; Chemical-industry-workers; Particulates; Eye-irritants; Respiratory-irritants; Occupational-exposure; Organic-vapors; Workplace-studies; Chromatographic-analysis; Analytical-methods
American Industrial Hygiene Association Journal