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Measurement of N-nitrosamine concentrations in NIOSH Diesel Exhaust/Coal Dust Study.

Authors
Choudhary G; Foley GD
Source
Cincinnati, OH: U.S. Department of Health and Human Services, Public Health Service, Centers for Disease Control, National Institute for Occupational Safety and Health, 1983 Jan; :1-27
Link
NIOSHTIC No.
00165834
Abstract
Measurements were taken of N-nitrosamine concentrations present in the animal chambers used during the NIOSH Diesel Exhaust/Coal Dust study. Monthly, and sometimes weekly, samples were taken. Samples were taken over 2 to 7 hours. The following nitrosamines were sought: N-nitrosodimethylamine (62759) (NDMA), N- nitrosodiethylamine (55185) (NDEA), N-nitrosodipropylamine (621647) (NDPA), N-nitrosodibutylamine (924163) (NDBA), N-nitrosopiperidine (100754) (NPIP), N-nitrosopyrrolidine (930552) (NPYR), N- nitrosomorpholine (59892) (NMOR), and N-nitrosodiphenylamine (86306) (NDPhA). Only NDMA, NDEA, and NDPA were detected above the detection limits of the system, 6.0 nanograms/cubic meter (ng/m3). Chambers containing either diesel exhaust or diesel exhaust plus coal dust most often contained NDMA, NDEA, or NDPA. Low levels of NDMA were occasionally found in chambers containing coal dust and clean air. Values obtained from the monthly samples collected during the earlier part of the study did not show any definite trend of variation. Precursors of nitrosamine formation were present in and prior to the exposure chambers, as indicated by the conversion of nitrosatable amines in samplers into the corresponding nitrosamine. The authors conclude that the observed nitrosamines appear to occur subsequent to diesel exhaust emission from the engine.
Keywords
NIOSH-Author; Diesel-exhausts; Diesel-emissions; Diesel-engines; Carcinogens; Particulate-dust; Airborne-particles
CAS No.
62-75-9; 55-18-5; 621-64-7; 924-16-3; 100-75-4; 930-55-2; 59-89-2; 86-30-6
Publication Date
19830101
Document Type
Other
Fiscal Year
1983
NTIS Accession No.
PB87-163515
NTIS Price
A03
NIOSH Division
DPSE
Source Name
National Institute for Occupational Safety and Health
State
OH
Page last reviewed: August 16, 2019
Content source: National Institute for Occupational Safety and Health Education and Information Division