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Health hazard evaluation report: HETA-84-415-1688, Precision Castparts Corporation, Portland, Oregon.
Cincinnati, OH: U.S. Department of Health and Human Services, Public Health Service, Centers for Disease Control, National Institute for Occupational Safety and Health, HETA 84-415-1688, 1986 May; :1-33
A cross sectional evaluation of semen quality (sperm concentration, pH, volume, viability, motility, velocity and morphology) was made among men employed at the Precision Castparts Corporation (SIC- 3369), Portland, Oregon in response to a management request to evaluate effects of exposure to 2-ethoxyethanol (110805) (2EE). About 80 male workers were potentially exposed to 2EE, used as a binder in investment casting. Full shift breathing zone airborne exposures to 2EE ranged from not detectable to 23.8 ppm. The average sperm count per ejaculate among the exposed workers was significantly lower than that of the unexposed comparison group, 113 versus 154 million sperm/ejaculate. Average sperm concentrations of both groups were significantly lower than the average for other occupational populations. The authors conclude that there is a possible effect of 2EE exposure on sperm count among these workers, but other factors may be affecting semen quality of both exposed and unexposed workers. Given the known testicular toxicity of 2EE in animals, limiting exposure to 2EE to the fullest extent feasible is recommended. The incidence of reproductive problems among the exposed workers should be followed. Personal protective equipment should be evaluated. The ventilation systems in all investment rooms should be checked and evaluated for effectiveness. A continuous program of industrial hygiene assessment is to be instituted, and the use of 2EE in the slurry mix is to be discontinued.
NIOSH-Author; NIOSH-Health-Hazard-Evaluation; NIOSH-Technical-Assistance-Report; Region-10; HETA-84-415-1688; Ethanols; Reproductive-hazards; Reproductive-system-disorders; Metal-industry-workers; Hazard-Unconfirmed; Author Keywords: Foundries, except Aluminum and Copper; 2-Ethoxyethanol; Ethylene Glycol Monoethyl Ether; 2-Ethoxyacetic Acid; Metal Casting; Semen Quality; Reproductive Health
Field Studies; Hazard Evaluation and Technical Assistance
NTIS Accession No.
National Institute for Occupational Safety and Health
Page last reviewed: April 12, 2019
Content source: National Institute for Occupational Safety and Health Education and Information Division