Extent of industrial exposure to epichlorohydrin, vinyl fluoride, vinyl bromide and ethylene dibromide.
Am Ind Hyg Assoc J 1980 Jul; 41(7):463-468
Results of industrial hygiene surveys for exposure to epichlorohydrin (106898), vinyl-fluoride (75025), vinyl-bromide (593602), and ethylene-dibromide (106934) were evaluated. The initial survey obtained information on process, production activity, potential exposures, and worker exposure. In depth surveys were used to determine 8 hour time weighted averages. A literature review caused NIOSH to conclude that exposure risks may include carcinogenesis, mutagenesis, and sterility in humans. Processes involved either took place in the open and outside or in closed buildings. Potential epichlorohydrin exposure ranged from nondetectable to 2.1 parts per million. Production operations were located out of doors with automated operations monitored from a control room. The potential exposure to epoxy resin was less for the production operations. The highest level found was less than 0.8ppm. Processess were located both indoors and outside with ventilation controls. Vinyl-fluoride could not be measured due to interference from difluoroethane. Vinyl-bromide ranged from 0.1 to 0.4ppm. Higher levels were found in laboratory analysis and loading operations. The greatest potential for exposure was related to open system operations and specifically the taking of quality control samples. The author concludes that currently the primary control for each operation is closed processing of chemicals. Use of personal protection, ventilation systems, and safe work practices are recommended.
NIOSH-Author; Organophosphorous-compounds; Organophosphorous-insecticides; Chronic-toxicity; Insecticides; Metabolites; Organic-compounds; Organic-chemicals; Metabolism; Insecticide-poisoning; Metabolic-study; Acute-toxicity
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American Industrial Hygiene Association Journal