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Health hazard evaluation report: HETA-80-035-1635, Bofors-Nobel/Lakeway Corporation, Muskegon, Michigan.
Singal M; Lee SA
Cincinnati, OH: U.S. Department of Health and Human Services, Public Health Service, Centers for Disease Control, National Institute for Occupational Safety and Health, HETA 80-035-1635, 1985 Nov; :1-25
Environmental and breathing zone samples were analyzed for dichlorobenzidine (91941), oryzalin (19044883), and dinitrochlorobenzene (97007) at Bofors/Nobel/Lakeway Corporation (SIC-2865), Muskegon, Michigan in November, 1980, February, 1981, and August, 1982. The evaluation was requested by the union local to investigate dermatitis, possible reproductive effects, and reported bladder cancer cases among the employees. Thirty six workers were interviewed by questionnaire. Medical records were reviewed. Urine samples were obtained before and after cleanup operations and analyzed for dichlorobenzidine. Breathing zone oryzalin and dichlorobenzidine concentrations averaged 28 and 0.9 micrograms per cubic meter, respectively. Full shift skin exposures to dichlorobenzidine averaged 6.3 micrograms per 25 square centimeters. Dichlorobenzidine surface contamination was found in the pack/out locker room; no dinitrochlorobenzene was detected. No adverse reproductive effects were reported. Fifty three percent of workers with potential dinitrochlorobenzene exposure and 31 percent without exposure reported skin problems. Ten cases of bladder cancer, with a mean latency of 13.3 years, were documented. Before cleanup operations began, 68 percent of the exposed workers had detectable urinary dichlorobenzidine; after cleanup, this was reduced to 28 percent. The authors conclude that there is a hazard from dichlorobenzidine. Recommendations include improving housekeeping procedures and possibly modifying production procedures to reduce dinitrochlorobenzene exposure.
NIOSH-Author; NIOSH-Health-Hazard-Evaluation; NIOSH-Technical-Assistance-Report; Hazards-Confirmed; Chemical-manufacturing-industry; Region-5; Reproductive-effects; Air-contamination; HETA-80-035-1635
91-94-1; 19044-88-3; 97-00-7
Field Studies; Hazard Evaluation and Technical Assistance
NTIS Accession No.
National Institute for Occupational Safety and Health
Page last reviewed: April 12, 2019
Content source: National Institute for Occupational Safety and Health Education and Information Division