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Progress Report. Lung Cancer Mortality Among Underground Uranium Miners With Low Lifetime Exposures To Radon Daughters.
A progress report was presented on a survey of lung cancer mortality in underground uranium (7440611) miners (SIC-1094) with low lifetime exposures to radon (10043922) daughters. The survey was an extension of an earlier United States Public Health Service (USPHS) survey. The cohort consisted of 3,362 white males and 780 American Navajo Indians who mined uranium on the Colorado Plateau between 1950 and 1963. The USPHS survey found elevated standardized mortality ratios (SMR) in white miners of 482 for lung cancer, 409 for tuberculosis, 331 for accidents, 324 for nonmalignant respiratory disease, and 262 for renal sclerosis. White miners had an all cause SMR of 158. The American Indian cohort members also had a significantly elevated risk of death from lung cancer, SMR 423. Risk of death from all causes was in deficit, SMR 86. The primary objective in continuing the study was to quantify lung cancer risk through 1982 according to radon daughter exposures. The authors note that vital status follow up from 1977 through 1982 will be accomplished using routine NIOSH methods. Exposures to radon daughters documented after 1969 will be added to the existing exposure records. Special attention will be given to lung cancer mortality risks for cohort members having lifetime exposures less than 120 working level months. A questionnaire has been developed to collect data in four areas: smoking history, occupational history, medical history, and a brief food frequency history. A total of 400 additional deaths among cohort members has been discovered.
Mortality-rates; Mining-industry; Radiation-exposure; Pulmonary-system; Occupational-exposure; Exposure-levels; Biological-effects; Industrial-exposures;
Infectious Diseases; Disease and Injury; Asthma and Chronic Obstructive Pulmonary Disease; Pulmonary-system;
Proceedings of the Third NCI/EPA/NIOSH Collaborative Workshop: Progress on Joint Environmental and Occupational Cancer Studies
Page last reviewed: April 12, 2019
Content source: National Institute for Occupational Safety and Health Education and Information Division