Vinyl Acetate - Physical And Chemical Analysis No. 278.
NIOSH 1978:8 pages
A gas chromatographic method for the analysis of vinyl-acetate (108054) in air is reviewed. The method involves drawing a known volume of air through a tube containing Chromosorb-107 to trap the vinyl-acetate present. The tube is thermally desorbed into a 200 milliliter chamber. An aliquot of the desorbed vapor is injected into a gas chromatograph. The area of the resulting peak is determined and compared with areas obtained from the injection of standards. The working range, sensitivity, and detection limit of the system are described. Interference factors are discussed. It is noted that any substance which has the same retention time as vinyl- acetate at the same operating conditions is an interference; retention time data on single or multiple columns cannot be considered proof of chemical identity. Results are reported which show the pooled relative standard deviation of the sampling and analytical methods for 50 samples collected with calibrated personal sampling pumps from humid atmospheres over the concentration range from 8 to 200 milligrams/cubic meter (mg/m3) to be 8.1 percent. Under the most adverse conditions tested, with 83 percent humidity, it is reported that the breakthrough volume was 4.0 liters when an atmosphere of vinyl-acetate at 113mg/m3 was sampled at 0.125 liter/minute. Advantages of the system include its small size and portability; disadvantages are also noted. The precision of the method is limited by the reproducibility of the pressure drop across the sampling tube. In addition, the amount of sample that can be taken is limited by the capacity of the sampling device. The apparatus and reagents required for the method are listed. Procedures for cleaning of equipment, collection and shipping of samples and their analysis, including gas chromatographic conditions, are detailed. Calibration and standardization are also discussed.
NIOSH-Author; Analytical-chemistry; Laboratory-techniques; Chromatographic-analysis; Laboratory-equipment; Ventilation; Equipment-design; Lung; Exposure-methods; Polymerization;
Unpublished Report, Measurement Research Branch, NIOSH, U.S. Department of Health, Education and Welfare, Cincinnati, Ohio, 8 pages, 1 reference