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Engineering and other health hazard controls in oral contraceptive tablet making operations.

Authors
Anastas MY
Source
Cincinnati, OH: U.S. Department of Health and Human Services, Public Health Service, Centers for Disease Control, National Institute for Occupational Safety and Health, CT-105-4, 1984 Sep; :1-94
NIOSHTIC No.
00145199
Abstract
A survey of health hazard controls in oral contraceptive tablet making (SIC-2834) operations was conducted. Four facilities were included in the survey. Engineering controls included using hoods while weighing pure steroids, local and general ventilation, material transfer systems in granulation and tablet forming operations, and using powder feed systems in tablet forming operations. Breathing zone estrogen and progestogen concentrations in granulation operations ranged from 0.15 to 1.04 and from 1.39 to 18.9 micrograms per cubic meter (microg/m3), respectively. Estrogen and progestogen concentrations in tablet forming operations were progestogen concentrations in packaging operations were 0.02 to 0.11 and 0.20 to 0.72microg/m3, respectively. All facilities utilized environmental and medical monitoring. Workers in granulation, tablet forming, and packaging operations were protected from exposure to steroids by respirators, coveralls, gloves, and overshoes. All facilities emphasized personal hygiene (frequent showering and changes of protective clothing). Job rotation was practiced at two facilities and good housekeeping was practiced at all facilities. The author notes that all facilities offer intensive training and education programs in health hazards, safety, and personal protective equipment associated with each job title.
Keywords
NIOSH-Author; Monitors; Protective-equipment; Lung; Lung-burden; Inhalants; Respiratory-irritants; Respiratory-protection; NIOSH-Survey; Field-Study; Control-technology
Publication Date
19840901
Document Type
Field Studies; Control Technology
Fiscal Year
1984
NTIS Accession No.
PB85-220739
NTIS Price
A06
Identifying No.
CT-105-4
NIOSH Division
DPSE
Priority Area
Control-technology
SIC Code
2834
Source Name
National Institute for Occupational Safety and Health
State
OH
Page last reviewed: December 28, 2020
Content source: National Institute for Occupational Safety and Health Education and Information Division