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Carcinogenic Potential Of Condensed Pyrolysis Effluents From Iron Foundry Casting Operations, Volume II.
Shellenberger TE; Garner FM; Plankenhorn LJ
NIOSH 1984 Oct:195 pages
Data tabulations for a carcinogenic bioassay of condensed effluents obtained from iron foundry casting operations that used hamsters as the test species are presented. The tables include sample collected rate, pH of collected samples, solubility of foundry samples in water and cyclohexane, and the elemental composition of furan (110009), urethane (51796), shell sand, and green sand effluents. Cumulative hamster mortality and survival data are presented. Data on the incidence of pharmacotoxic signs such as wheezing, dyspnea, polypnea, hunched back, ataxia, soft feces, squinting eyes, alopecia and soiled anal areas occurring during weeks 8 through 116 in male hamsters and weeks 6 through 102 in females are tabulated. Data tabulations of mean body weights of males for weeks 1 through 111, and weeks 11 through 102 for females are presented. Histopathological findings in the larynx, trachea, and lung during a preliminary acute range finding study are summarized. Cumulative mortality and body weight changes during the acute study are presented. Photographs and diagrams of the samplers and sampling trains are also presented.
NIOSH-Contract; Pyrolysis; Iron-oxide-fumes; Iron-working-industry; Data-processing; Quantitative-analysis; Lung-fibrosis; Equipment-design; Pharmacodynamics; Toxicology; Contract-210-78-0033;
NTIS Accession No.
Experimental Toxicology Branch, Division of Biomedical and Behavioral Science, NIOSH, U.S. Department of Health and Human Services, Cincinnati, Ohio
Page last reviewed: November 6, 2020
Content source: National Institute for Occupational Safety and Health Education and Information Division