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Health hazard evaluation report: HETA-81-301-1467, United Farm Workers of America, AFL- CIO, Salinas, California.
Coye MJ; Barnett P; Midtling J; Lowry L
Cincinnati, OH: U.S. Department of Health and Human Services, Public Health Service, Centers for Disease Control, National Institute for Occupational Safety and Health, HETA 81-301-1467, 1984 May; :1-19
Exposures to mevinphos (7786347) among 44 field workers (SIC-0161) in Salinas, California were investigated after an illness outbreak on April 23, 1981. The evaluation was requested by the United Farm Workers of America, AFL CIO, on behalf of 31 affected workers. Some 29 workers developed various symptoms after working for several hours in a field that had been sprayed early that morning with mevinphos. Two of the workers were hospitalized because of low plasma cholinesterase (ChE) values and respiration problems. The other 29 were periodically tested for up to 12 weeks for both plasma and red blood cell (RBC) ChE. The most commonly reported symptoms included eye irritation, headache, vision disturbances, dizziness, nausea, fatigue, chest pain or shortness of breath, skin irritation, eyelid and arm fasciculation, excessive sweating, and diarrhea. ChE regeneration was generally completed by 14 days after the exposure. The initial inhibition was 15.6 percent for plasma ChE and 5.6 percent for RBC ChE. Plasma ChE fell another 7.3 percent before regeneration began, while RBC ChE values remained stable until regeneration. The regeneration rates were 1.20 and 0.43 percent per day for plasma and RBC ChE, respectively. The authors conclude that the field workers had been exposed to excessive amounts of mevinphos. They recommend the use of sequential ChE determinations after a potential exposure to confirm ChE inhibition in persons without available baseline tests. Warning signs should be posted around fields that have been sprayed, and water should be available near the fields for emergency washing purposes.
NIOSH-Author; NIOSH-Health-Hazard-Evaluation; NIOSH-Technical-Assistance-Report; Hazards-Confirmed; Agricultural-industry; Region-9; Organophosphorous-compounds; Pesticides; Cholinesterase-inhibitors; Respiratory-irritants; Acute-exposure; Clinical-symptoms; HETA-81-301-1467; Author Keywords: Vegetables and Melons; Organophosphates; Mevinphos; Phosdrin; Cholinesterase; Pesticides
Field Studies; Hazard Evaluation and Technical Assistance
NTIS Accession No.
National Institute for Occupational Safety and Health
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Page last reviewed: April 12, 2019
Content source: National Institute for Occupational Safety and Health Education and Information Division