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Statement On Proposed Permanent Standard For Vinyl Chloride.

Key MM
Paper Presented at the OSHA Hearing, U.S. Department of Labor, June 25, 1974, 1974:55-60
A proposed permanent standard for vinyl-chloride (75014) (VC) exposure is reviewed. The extent of the problems of developing effective controls for exposures to VC among polyvinyl-chloride (9002862) (PVC) workers is assessed. Establishment of a surveillance network to determine the number and distribution of cases of liver angiosarcoma, its relationship to VC or PVC exposure, the subsequent confirmation of 18 cases of angiosarcoma of the liver in PVC production workers, and 1 case in VC production are described. Factors are considered for the occurrence of angiosarcomas, including job duties, degree and length of exposure, latency period, and age at death. Other health effects of exposure to VC are assessed, including disabling liver fibrosis. NIOSH surveillance activities are cited; they include a cohort mortality study of VC workers, compilation of an extensive bibliography of world literature on VC, a mortality study at five PVC production facilities, and a medical cross section survey of current and former polymerization workers. Sampling and analysis procedures for VC determinations are discussed. Adequate respiratory protection and types of equipment are considered. NIOSH efforts to determine actual worker exposures to VC and PVC are noted. Walk through surveys of polymerization and fabrication facilities to determine major sources of VC release are described. The author concludes that in view of the finding of appreciable concentrations of VC in fabrication operations and reports of angiosarcoma in monomer production and secondary manufacture, exposure to VC should be controlled wherever it is encountered in the workplace.
Health-standards; Exposure-limits; Regulations; Industrial-chemicals; Plastics; Epidemiology; Quantitative-analysis; Safety-equipment;
75-01-4; 9002-86-2;
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Paper Presented at the OSHA Hearing, U.S. Department of Labor, June 25, 1974
Page last reviewed: February 11, 2022
Content source: National Institute for Occupational Safety and Health Education and Information Division