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Briefing On Styrene-Butadiene.
NIOSH 1976:232 pages
The proceedings of an April 1976 panel discussion on potential hazards among styrene (100425) and butadiene (106990) workers is presented. Employees of factories making styrene butadiene rubber are apparently experiencing an excess of mortality from leukemia and lymphoma. Epidemiological evidence is cited that shows leukemia incidences of 11.1, 10.7, and 13.2 per 100,000 in three counties in Texas that contain these factories. The leukemia rate for the general US population is 8.8 per 100,000. Case histories of leukemia occurring at two rubber manufacturing facilities in Texas are described. Thus far, six cases of leukemia and three of lymphoma among workers have been detected. The lymphomas have an apparent latency period of 20 to 30 years. Current industrial health surveys are examined. Irritation of mucous membranes occurs with styrene exposure of 50 to 100 parts per million (ppm). Such symptoms have been found in 18 percent of workers surveyed. Specific exposures include cleaning reactor vessels and stripping columns without respiratory protection and eating in rooms where exposure to toxic chemicals occurs. Attempts to determine the toxic chemicals in rubber manufacturing are described. Antioxidants may be among the most toxic chemicals used in the process. Efforts to reduce employee exposure are discussed. The current OSHA standards for butadiene and styrene are 1,000 and 100ppm, respectively. Planned blood studies among workers are noted. The authors conclude that more information on the hazards associated with the process is urgently needed.
NIOSH-Author; Mortality-data; Epidemiology; Biological-effects; Occupational-exposure; Toxicology; Occupational-hazards; Blood-analysis;
NIOSH, Public Health Service, U.S. Department of Health, Education and Welfare, 232 pages
Page last reviewed: September 2, 2020
Content source: National Institute for Occupational Safety and Health Education and Information Division