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Technical Assistance Report No. TA-79-51, West Virginia University, West Virginia.
Cincinnati, OH: U.S. Department of Health and Human Services, Public Health Service, Centers for Disease Control, National Institute for Occupational Safety and Health, TA 79-51, 1980 Jul; :1-17
Personal and area air samples were analyzed for common laboratory solvents used in radioimmune assays at the Department of Pharmacology, West Virginia University Medical Center (SIC-0867), Morgantown, West Virginia in October 1979. The evaluation was requested by a representative of the Department out of concern for chronic excessive exposure to the solvents. Samples were analyzed for acetone (67641), benzene (71432), chloroform (67663), 2,2,4- trimethylpentane (540841), methanol (67561), and toluene (108883). Work practices and ventilation system performance were evaluated. Air concentrations of the solvents were below all relevant federal standards. Good work practices were used by the laboratory technicians. Storage practices were deficient. Some chemicals were stored overhead, and used scintillation vials were emptied into large containers that were not sealed or ventilated. Laboratory hoods had inadequate face velocities for working with toxic chemicals. The author concludes that although airborne solvent concentrations were below federal standards, there is a risk of excessive exposure due to poor handling and storage of chemicals and the defective hoods. Recommendations include adjusting hoods to conform to NIOSH standards, not storing chemicals overhead, and proper and prompt disposal of used scintillation vials.
NIOSH-Author; NIOSH-Technical-Assistance-Report; Hazards-Unconfirmed; Laboratories; Air-quality-measurement; Toxic-vapors; Employee-exposure; Control-methods; Health-hazards; TA-79-51; Region-3
67-64-1; 71-43-2; 67-66-3; 540-84-1; 67-56-1; 108-88-3
Field Studies; Technical Assistance
NTIS Accession No.
National Institute for Occupational Safety and Health
Page last reviewed: April 12, 2019
Content source: National Institute for Occupational Safety and Health Education and Information Division