A technique was developed to separate mixtures of particulate inorganic arsenic compounds and arsine (7784421), and to detect arsenic-trioxide (1327533) vapor. A 13 millimeter (mm) filter/charcoal tube system, a 37mm filter, and a 37mm carbon treated filter were compared for particulate and arsine collection characteristics. Experiments were conducted in exposure chambers and at a battery manufacturing facility, and arsenic was measured with atomic absorption spectrometry. Algorithms were used to resolve the arsenic species. The experimental technique consisted of a sampling train with a 1.2mm inlet orifice, a 13mm cellulose ester filter without back up pad, and a standard 150 milligram charcoal tube. Air was drawn through the inlet, filter, and tube at significant difference between the collection characteristics of the 13mm filter/charcoal tube system and the 37mm filter; collection efficiency was 1.0. No measurable arsine was collected on any of the filters. In the field study, the particulate collection efficiencies of the three filters were identical; however, the 13mm filter collected less total arsenic than the 37mm filter, which in turn collected less than the carbon treated filter. The carbon treated filter had the highest arsenic-trioxide vapor efficiency at 98 percent, followed by the 37mm filter/back up pad combination at 81 percent. Collection efficiency of the 13mm filter was 35 percent; however, the arsenic-trioxide vapor which penetrated the 13mm filter was collected with 96 percent efficiency by the charcoal tube. The carbon treated filter was unable to detect arsine. Both the 13mm and 37mm filters, when used with the charcoal tube, were able to detect arsine with 100 percent efficiency. The authors conclude that the 13mm filter/charcoal tube sampling train effectively separates particulate arsenic from arsine and can be used to collect personal exposure data. Used by itself, the carbon treated filter is a more efficient collector of arsenic-trioxide vapor than the classical filter method, and is an equivalent collector of particulate arsenic.