Mortality and industrial hygiene study of workers exposed to styrene: interim report.
Okun AH; Beaumont JJ; Meinhardt TJ; Crandall MS
Mortality among employees exposed to styrene (100425) was investigated in fiberglass reinforced boat manufacturing facilities (SIC-3732). To support this study, seven facilities were surveyed to determine the employees' full shift time weighted average (TWA) to styrene exposure. TWA styrene exposures were evaluated according to jobs performed at all facilities, and 12 job performance areas were examined. Several samples from each facility were analyzed for styrene concentrations. Mortality and cause of death of workers was examined in two facilities with a total worker population of 5,368 at the time of this survey. Demographic data was also collected. The composite mean concentrations of styrene for the facilities surveyed ranged from 35.9 to 90.0 parts per million (ppm) (average 63.8ppm) for 464 samples. The two facilities being used for cohort mortality studies showed mean concentrations of 42.5 and 71.7ppm and ranges of 7.3 to 84.7 and 10.4 to 183ppm, respectively. The mean TWA styrene exposures by job, performed at all facilities, averaged 63.3ppm with the highest mean concentration occurring in the stringer installation area at 86.4ppm, and lowest in the paste mixer area, at 21.4ppm. Mortality checks among the 5,368 employees in the two facilities selected for cohort study revealed 3 percent deaths (182 subjects); 11 deaths were due to lung cancer, 4 due to genital cancer, and 13 due to cancers of other organs. The only increased cancer was male genital cancer. Of the four deaths in this category, three were prostatic and one testicular.
NIOSH-Author; Aromatic-hydrocarbons; Chemical-properties; Employee-exposure; Industrial-hygiene; Mortality-data; Toxic-effects; Industrial-medicine; Physiological-response; Styrenes; Fibrous-glass; Boat-manufacturing-industry
Division of Surveillance, Hazard Evaluations and Field Studies, NIOSH, Cincinnati, Ohio, 24 pages, 36 references