NIOSH 1978 Oct:32 pages
An analytical method was developed for the determination of 1-chloro- 1-nitropropane (52625088) in airborne samples. The protocol consisted of the analysis of 18 spiked samples containing 50, 100, and 200 percent of the OSHA standard of 20 parts per million and 18 dynamically generated samples with the same volume. Precision and accuracy of the method and storage stability of the samples were assessed. A known volume of air was drawn through a tube containing Chromosorb 108, which was then transferred to vials and the 1-chloro- 1-nitropropane was desorbed with ethyl-acetate. Aliquots of solution were then injected into gas chromatograph with a flame ionization detector. The method was validated over the range from 51 to 206 milligrams per cubic meter. The upper limit of the range was dependent on the absorptive capacity of the Chromosorb 108 which varied with chemical concentrations in the air. The coefficient of variance was 0.094. The authors conclude that the advantages of the method are that the sampling device is small, portable, and involves no liquids. Interferences are minimal. A disadvantage is that the sample size is limited because of the capacity of the tube.
NIOSH-Analytical-Method; Analytical-methods; Sampling; Chromatographic-analysis; Chemical-analysis; Standards; Analytical-instruments; Chemical-properties; Analytical-Method; Standards-Completion-Program;
NTIS Accession No.
Ten NIOSH Analytical Methods, Set-6, Division of Physical Sciences and Engineering, NIOSH, Cincinnati, Ohio, NTIS PB-288-629, 32 pages, 7 references