The dermatologic, pulmonary, and neurologic effects on workers in the roofing trade (SIC-1761) were evaluated. The study was requested by Local 33 of the United Union of Roofers, Waterproofers, and Allied Workers in Boston, Massachusetts. A comprehensive assessment of 55 active and retired union members was performed in March 1982. The workers ranged in age from 21 to 76 years, with a mean of 43. Subject received an occupational and general health questionnaire, pulmonary function tests, chest X-rays, a physical examination, blood count, liver profile, and neuropsychological testing. Work related injuries such as burns, falls, back injuries, and accidents were reported frequently. Headache and lightheadedness were the most frequent neurological complaints. Skin carcinoma was found in two subjects. Chest X-ray abnormalities were seen in 50 percent of subjects. The prevalence of bilateral pleural thickening was about 50 percent after 10 years. Pulmonary function tests were acceptable in 52 of the subjects. Pulmonary function declined consistently with years worked. The authors conclude that roofers experience respiratory, neuropsychological, and skin disorders associated with their work. A larger study is needed to quantify the extent of the problems.