Review of the Literature on Crystalline Silica.
NIOSH 1983 Jun:83 pages
Literature and data encompassing crystalline silica (14808607) is reviewed. Group results of medical tests on silicosis, and retrospective studies on cancer and silicosis are discussed. The human effects of silicosis, its complications, associated diseases, and diagnostic procedures are described. Sandblasting practices are related to silicosis. Potential techniques for the evaluation of silicotics are outlined. Animal studies and studies of effects of human exposures are cited. Swedish industries are classified by dust exposure concentration. Percentages of exposed workers are tabulated. Dust control measures in stone working occupations are listed. Sampling and analysis procedures by the respirable mass method and by X-ray diffraction techniques are discussed. Properties of respirable dust collection filters are presented. Analysis of quartz in foundry dusts is examined. Information gaps and areas where further data is needed are noted. Occupational data for areas of exposure to crystalline silica are appended. The importance of definitive evaluation of the individual research methods and their interrelationship is stressed. The authors conclude that the disease mechanism for crystalline silica has not been determined, and further research is needed.
NIOSH-Author; Silica-dusts; Pathogenesis; Sampling-methods; Dust-exposure; Disease-incidence; Exposure-levels; Toxicology; Disease-prevention;
NTIS Accession No.
NIOSH, Public Health Service, U.S. Department of Health and Human Services, NTIS PB83-238-733, 83 pages, 122 references