Elemental mercury exposure: peripheral neurotoxicity.
Levine-SP; Cavender-GD; Langolf-GG; Albers-JW
Br J Ind Med 1982 May; 39(2):136-139
The effect of mercury (7439976) vapor exposure on the ulnar nerve was determined in human subjects. Eighteen asymptomatic male workers from a mercury cell chlorine plant were evaluated for mercury exposure by urinalysis and for compound muscle action potential, sensory nerve action potential, negative peak amplitude, motor and sensory distal latency, and maximum motor velocity (max MCV) of the ulnar nerve by conventional techniques. Average urine mercury concentrations ranged from 0.02 to 0.45 milligrams per liter. The mean compound muscle action potential amplitude was low and motor latency long when compared with normal values, although no individual amplitude was outside the normal range. Workers with prolonged distal latencies had significantly higher urine mercury concentrations when compared to those with normal latencies. Significant correlations between increasing urine mercury concentrations and prolonged motor and sensory distal latencies were established. The authors conclude that exposure to inorganic mercury can affect both motor and sensory peripheral nerve conduction in a manner consistent with a mild sensorimotor neuropathy.
NIOSH-Publication; NIOSH-Grant; Heavy-metals; Occupational-medicine; Mercury-poisoning; Nervous-system-disorders; Nerve-function; Health-surveys
Industrial & Operations Engr University of Michigan Industrial & Operations Engr Ann Arbor, Mich 48109
British Journal of Industrial Medicine
University of Michigan at Ann Arbor