The health effects associated with trichloropropane (25735299) exposure were reported. The chemical and physical properties, as well as the various uses of trichloropropanes, were presented. The biological processes of absorption, distribution, metabolism, and modes of degradation were described. Effects on human skin, eyes, respiratory system, central nervous system and the major organs, following exposures to trichloropropanes, 1,2-dichloropropanes, and tetrachloroethylene (127184), were reviewed. Acute and chronic animal toxicology data and results of carcinogenicity, mutagenicity, and teratogenicity testing were reported.
NIOSH, U.S. Department of Health and Human Services, Franklin Research Center, Silver Spring, Md., 84 pages, 104 references