A NIOSH standard for worker exposure to carbon-tetrachloride (56235) is reviewed. Control of air concentrations in the workplace so they do not exceed 2 parts per million (ppm) in 45 liters is discussed. Medical requirements of the standard, including preplacement and annual physicals, counseling regarding use of alcohol and barbiturates, and the maintenance of medical records also are discussed together with labelling requirements for shipping and storage containers, and for areas of occupational exposure. Clothing and equipment are described for protection of eyes and respiratory system, together with gloves, aprons, and footwear. The need for employee education regarding the hazards, signs, and symptoms of overexposure, emergency procedures, and proper conditions and precautions for safe use of carbon tetrachloride is considered. Work practices, including the control of airborne contamination, contact with skin and eyes, emergency procedures, cleaning of spills, housekeeping procedures, personal hygiene, access to regulated areas, and control of soiled clothing are described. Sanitation requirements are presented for washing facilities, clothing and locker facilities, and smoking restrictions. Record keeping and exposure monitoring procedures are reviewed. The author notes that the carbon-tetrachloride standard is designed to protect the health and safety of workers up to 10 hours per day, 40 hours per week, over a working lifetime.