The application of a computer-controlled time discrimination performance to problems in behavioral toxicology.
Johnson-BL; Anger-WK; Stezer-JV; Xintaras-C
Behavior Toxicology; :129-153
Studies concerning the psychophysics of time discrimination are reviewed along with the effects of chlorpromazine (50533) and carbon- monoxide (630080) on time discrimination. A computer system for investigating the effects of such chemical contaminants is described along with the behavioral testing chamber used in the experiments. Time discrimination thresholds are described for three female Macaca mulatta monkeys. The individual effects of chlorpromazine and carbon-monoxide on time discrimination by the animals also is reviewed. The authors conclude that knowledge of the effects of toxic agents found in community and occupational environments is essential if meaningful exposure limits are to be developed.
Animal-studies; Exposure-chambers; Toxic-gases; Exposure-limits; Analytical-methods; Behavior; Exposure-methods
Behavior Toxicology (reprint)