An Analysis of Maximal Expiratory Flow-Volume Curves Based on an Analytical Model of Lung Mechanics.
NIOSH 1976 Apr:14 pages
The testing and validation of a mathematical model of the mechanical properties of the lungs used in studying the maximal expiratory flow volume curve is reviewed. Tests based on alterations to viscous flow losses, airway mechanics, and viscoelasticity are described. Predictions of maximal expiratory flow volume curves and static pressure volume curves for excised dog or normal human lungs at post mortem are discussed. Predictions of maximal expiratory flow volume curves and other lung mechanics data for man based on breathing mixtures of differing density and viscosity also are discussed. Data obtained on normal humans of varying age to establish empiric normal values and furnish material for the development of normal predictive values from the analytical model is examined. Preliminary steps in applying the modified analytical model to disease states are reviewed.
NIOSH-Contract; Contract-HSM-99-72-133; Mathematical-models; Biomechanics; Pulmonary-system; Pulmonary-function; Analytical-methods;
NTIS Accession No.
Asthma and Chronic Obstructive Pulmonary Disease; Disease and Injury; Pulmonary-system;
Health Service and Mental Health Association, NIOSH, Rockville, Md., 14 pages, 13 references