Intraneural connective tissue proliferation of the median nerve in the carpal tunnel.
Castelli-WA; Evans-FG; Diaz-Perez-R; Armstrong-TJ
Arch Phys Med Rehabil 1980 Sep; 61(9):418-422
The proliferation of the intraneural connective tissues of the median nerve in the carpal tunnel was studied. Segments from the median nerve were removed from the distal fourth of the right forearm and the carpal tunnel area of 23 embalmed human cadavers. Photomicrographs of the nerve cross sections were taken and the cross sectional area of the whole nerve was determined. The mean differences in the percentage of nerve fascicles plus perineuria, and of epineuria alone in the round and the flattened cross sections of the median nerve were calculated. The percentage of cross sectional area formed by fascicles plus perineuria in the round cross sections of the nerve was significantly greater in both males and females compared to the flat cross sections of the nerve within the carpal tunnel. In both males and females, the percentage of the cross sectional area formed by epineuria alone was significantly greater in the flat sections of the nerve than in the round ones. A proliferation of the intraneural connective tissue in the flattened sections of most nerves was noted and was mainly due to the proliferation of the epineural layers. The authors conclude that the proliferative increase of the intraneural connective tissue is a localized characteristic of the median nerve in the carpal tunnel and is a normal occurrence in males and females.
NIOSH-Publication; NIOSH-Grant; Humans; Nerve-tissue; Medical-research; Sex-factors; Nervous-system; Connective-tissue; Physical-properties; Nerve-fibers
Industrial & Operations Engr University of Michigan 2260 G G Brown Laboratory Ann Arbor, Mich 48109
Archives of Physical Medicine and Rehabilitation
University of Michigan at Ann Arbor, Ann Arbor, Michigan