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Walk-through survey report of the oral contraceptive manufacturing operations at Ortho Pharmaceuticals, Inc., Dorado, Puerto Rico.
Cincinnati, OH: U.S. Department of Health, Education, and Welfare, Public Health Service, Centers for Disease Control, National Institute for Occupational Safety and Health, IWS 85-12, 1979 Jul; :1-15
Worker exposures to estrogens were studied at Ortho Pharmaceuticals, Incorporated (SIC-2834) in Dorado, Puerto Rico, from May 16 to 17, 1978. The company was under consideration for inclusion in a NIOSH study of the health effects of occupational estrogen exposure. Approximately 115 of the employees at the facility were assigned to the estrogen manufacturing areas that were surveyed. The company had no formal safety and industrial hygiene program. Medical services were furnished by a local physician on a part time basis and one full time nurse. Personnel records provided demographic information, department assignments, and absence reports. Workers in the manufacturing area had the greatest potential for estrogen exposure. Estrogen exposures to packaging area operators, quality assurance technicians, and maintenance workers were intermittent and minimal. The authors conclude that this work force should not be used for a mortality study and a reproductive study due to limitations of personnel records, small number of exposed personnel, short exposure periods, exclusion of women from the manufacturing area, and the product exposure data limitations. They recommend that a decision regarding the inclusion of this facility in the in- depth medical or estrogen hazard survey be deferred until additional similar facilities are surveyed.
NIOSH-Author; NIOSH-Survey; Field-Study; Region-2; Health-surveys; Workplace-studies; Air-contamination; Health-services; Industrial-processes; Control-methods; Hormones; Chemical-manufacturing-industry
Field Studies; Industry Wide
NTIS Accession No.
National Institute for Occupational Safety and Health
Page last reviewed: September 2, 2020
Content source: National Institute for Occupational Safety and Health Education and Information Division