The NIOSH analytical method S180 for determining maleic-anhydride (108316) in air is described. Samples are collected in a midget bubbler, hydrolyzed to maleic-acid (110167), and analyzed by high pressure liquid chromatography with an ultraviolet detector at 254 nanometers. The working range of the method is 0.5 to 2.14 milligrams per cubic meter, the relative standard deviation is 0.63, and the detection limit is 15 micrograms per sample. Analytical apparatus, reagents and procedures are described and calculations are provided for determining sample concentrations. Data on stability, collection efficiency and recovery rates is included. The method was unsatisfactory due to inadequate sample stability.
NIOSH, Unpublished, Cincinnati, Ohio, 28 pages, 8 references