NIOSHTIC-2 Publications Search

Methyl-n-butyl ketone and peripheral neuropathy.

Authors
Mallov JS; Marceleno T; Fontaine R
Source
Cincinnati, OH: U.S. Department of Health, Education, and Welfare, Public Health Service, Centers for Disease Control, National Institute for Occupational Safety and Health, IWS 47-3, 1975 Jun; :1-23
Link
NIOSHTIC No.
00107091
Abstract
The neurotoxicity of methyl-butyl-ketone (591786) (MBK) is discussed. Animal toxicity studies and five case reports of peripheral neuropathy in exposed workers are reviewed. Results of neurologic examinations of 207 workers from four paint manufacturing companies (SIC-2851) are evaluated. The authors conclude that MBK can cause peripheral neuropathy in humans, even at concentrations as low as 100 parts per million. Proper engineering controls can reduce the hazards of exposure to MBK.
Keywords
NIOSH-Author; NIOSH-Survey; Field-Study; Region-5; Pesticides-and-agricultural-chemicals; Health-surveys; Workplace-studies; Air-contamination; Occupational-health-programs; Case-studies
CAS No.
591-78-6
Publication Date
19750601
Document Type
Field Studies; Industry Wide
Fiscal Year
1975
NTIS Accession No.
PB81-229981
NTIS Price
A03
Identifying No.
IWS-47-3
NIOSH Division
DFSCI
SIC Code
2851
Source Name
National Institute for Occupational Safety and Health
State
OH
Page last reviewed: September 4, 2020
Content source: National Institute for Occupational Safety and Health Education and Information Division