Spontaneous Abortion Studies: Role in Surveillance.
Kline-J; Stein-Z; Susser-M; Warburton-D
NIOSH 1980 Oct:279-292
The use of spontaneous abortion data to determine hazardous chemical exposure is discussed. The epidemiology of spontaneous abortion is reviewed in relation to exposure surveillance along with types of anomalies that can be found in the aborted material. Data from an earlier study of spontaneous abortions among wives of workers exposed to vinyl-chloride (75014) is included together with a retrospective evaluation of an epidemic of trisomy concept uses. The authors propose a three factor monitoring system to detect anomalies at spontaneous abortion, amniocentesis, and birth. They conclude that evaluation of the incidence of spontaneous abortion among a particular population can help identify hazardous exposures.
Reproductive-effects; Toxic-materials; Toxic-effects; Embryotoxicity; Disease-control; Occupational-exposure; Plastics;
Infectious Diseases; Disease and Injury;
Proceedings of a Workshop on Methodology for Assessing Reproductive Hazards in the Workplace, April 19-22, 1978, P.F. Infante and M.S. Legator, Eds. Division of Surveillance, Hazard Evaluations and Field Studies, NIOSH, U.S. Department of Health and Human Services