A Review of the Methodologic Approaches in the Assessment of an Association Between Vinyl Chloride Exposure and Reproductive Hazards.
NIOSH 1980 Oct:43-52
Studies on the reproductive effects of vinyl-chloride (75014) (VC) exposure are reviewed. VC related deaths among exposed worker populations are discussed along with the association between VC and cancer. The incidence of fetal deaths and malformations among offspring of exposed workers and laboratory animals is evaluated along with methodological limitations of various studies. Research on the mutagenicity of VC in bacterial cultures and plant systems is reviewed.
Reproductive-effects; Plastics; Occupational-exposure; Mortality-rates; Carcinogens; Embryotoxicity; Humans; Laboratory-animals; In-vitro-study;
Proceedings of a Workshop on Methodology for Assessing Reproductive Hazards in the Workplace, April 19-22, 1978, P.F. Infante and M.S. Legator, Eds. Division of Surveillance, Hazard Evaluations and Field Studies, NIOSH, U.S. Department of Health and Human Services