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Carcinogenicity and metabolism of azo dyes, especially those derived from benzidine.

Authors
Boeniger M
Source
Cincinnati, OH: U.S. Department of Health and Human Services, Public Health Service, Centers for Disease Control, National Institute for Occupational Safety and Health, DHHS (NIOSH) Publication No. 80-119, 1980 Jul; :1-141
Link
https://ntrl.ntis.gov/NTRL/dashboard/searchResults/titleDetail/PB81171027.xhtml
NIOSHTIC No.
00103469
Abstract
The carcinogenicity and metabolism of azo dyes derived from benzidine (92875) is presented. The metabolism of benzidine and azo compounds in humans and animals is discussed, and the disease incidence among workers in industries using azo dyestuffs is described. Industrial hygiene surveys performed to monitor the environment of azo dye workers and their urinary excretion of aromatic amines and benzidine are reviewed. Jobs involving dyestuff exposure and exposure to carcinogenic agents are identified. The author concludes that this study indicates the potential carcinogenicity of benzidine and the metabolites of benzidine derived dyes.
Keywords
NIOSH-Author; Oncogenesis; Biochemistry; Azo-dyes; Aromatic-hydrocarbons; Metabolism; Occupational-exposure; Industrial-hygiene; Air-sampling
CAS No.
92-87-5
Publication Date
19800701
Document Type
Numbered Publication
Fiscal Year
1980
NTIS Accession No.
PB81-171027
NTIS Price
A08
Identifying No.
DHHS (NIOSH) Publication No. 80-119
NIOSH Division
DSHEFS
Source Name
National Institute for Occupational Safety and Health
State
OH
Page last reviewed: May 11, 2023
Content source: National Institute for Occupational Safety and Health Education and Information Division