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Carcinogenicity and metabolism of azo dyes, especially those derived from benzidine.
Cincinnati, OH: U.S. Department of Health and Human Services, Public Health Service, Centers for Disease Control, National Institute for Occupational Safety and Health, DHHS (NIOSH) Publication No. 80-119, 1980 Jul; :1-141
The carcinogenicity and metabolism of azo dyes derived from benzidine (92875) is presented. The metabolism of benzidine and azo compounds in humans and animals is discussed, and the disease incidence among workers in industries using azo dyestuffs is described. Industrial hygiene surveys performed to monitor the environment of azo dye workers and their urinary excretion of aromatic amines and benzidine are reviewed. Jobs involving dyestuff exposure and exposure to carcinogenic agents are identified. The author concludes that this study indicates the potential carcinogenicity of benzidine and the metabolites of benzidine derived dyes.
NIOSH-Author; Oncogenesis; Biochemistry; Azo-dyes; Aromatic-hydrocarbons; Metabolism; Occupational-exposure; Industrial-hygiene; Air-sampling
NTIS Accession No.
DHHS (NIOSH) Publication No. 80-119
National Institute for Occupational Safety and Health
Page last reviewed: April 12, 2019
Content source: National Institute for Occupational Safety and Health Education and Information Division