Increased incidence of choroidal malignant melanoma occurring in a single population of chemical workers.
Smith-AB; Egan-E; Leffingwell-SS
Am J Ophthalmol 1980 Mar; 89(3):323-337
The incidence of choroidal malignant melanomas in workers at a chemical facility in West Virginia was studied. Three cases of choroidal melanoma that had occurred between 1972 and 1975 among workers were confirmed by histopathologic examination. In addition, an ophthalmologic survey was conducted with 591 active employees, 256 retired employees, and 302 comparisons. One retired employee with a choroidal malignant melanoma was identified, and one case of iris melanoma in an active employee was diagnosed. No choroidal melanomas were observed in the comparison population. The authors note that these findings represent a significantly greater occurrence of choroidal melanoma in the study population than would be expected in the general population.
NIOSH-Author; Eye-disorders; Chemical-exposure; Carcinogens; Tumorigenesis; Epidemiology; Histological-changes; Work-environment; Chemical-factory-worker
Daniel M. Albert, M.D., Howe Laboratory of Ophthalmology, Massachusetts Eye and Ear Infirmary, 243 Charles St., Boston, MA 02114
American Journal of Ophthalmology