Mortality experiences of insulation workers in the United States and Canada, 1943-1976.
Selikoff-IJ; Hammond-EC; Seidman-H
Ann NY Acad Sci 1979 Dec; 330(1):91-116
The mortality patterns of two cohorts of insulation workers exposed to asbestos (1332214) were analyzed. The larger cohort of 17,800 men on the rolls of the insulation workers' union in the U.S. and Canada on January 1, 1967 was studied through December 31, 1976. The other cohort of 632 male asbestos insulation workers in the New York and New Jersey metropolitan area was studied from 1943 to 1976. Workers from both countries had a significantly increased risk of death from cancer and asbestosis. The increases in death from cancer included lung cancer, pleural mesothelioma, peritoneal mesothelioma, and cancers of the esophagus, colon and rectum, larynx, oropharynx and kidney. Little increase in cancer and asbestosis mortality occurred in workers with less than 19 years of exposure; the period of latency between exposure onset and death was 20 or more years. Large increases in lung cancer occurred at 15 to 35 years from exposure onset while deaths from pleural and peritoneal mesothelioma were most common after 35 years. The authors recommend that studies on the effects of asbestos exposure should analyze the mortality experience of the individuals at risk at least 30 to 35 years from onset of exposure.
NIOSH-Publication; NIOSH-Grant; Pulmonary-system-disorders; Epidemiology; Construction-materials; Asbestos-dust; Mortality-data; Oncogenic; Latent-period; Risk-exposure; Organs; Lung-fibrosis; Mineral-wool; Data-analysis; Statistical-analysis; Death-certificates; Pathology
Community Medicine Mount Sinai School of Medicine Fifth Avenue and 100 Street New York, N Y 10029
Annals of the New York Academy of Sciences
Mount Sinai School of Medicine, New York, New York