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HHE determination report no. HHE-79-86-675, Tufts Medical School, Boston, Massachusetts.
Cincinnati, OH: U.S. Department of Health, Education, and Welfare, Public Health Service, Centers for Disease Control, National Institute for Occupational Safety and Health, HHE 79-86-675, 1980 Mar; :1-7
Environmental sampling and personal interviews were conducted on May 17 and June 6 and 7, 1979, at Tufts Medical School (SIC-8221), Boston, Massachusetts to determine the cause of an outbreak of angioneurotic edema. The dean of the medical school requested the evaluation on behalf of five affected employees. Samples for formaldehyde were below the OSHA limit of 3 parts per million. All of the affected employees had atopic histories, and one of the workers reported a family history of angioneurotic edema. Three of the employees believed that trauma or stress was responsible for their symptoms. The authors conclude that the outbreak of angioneurotic edema was probably not caused by chemical exposures at this facility. Certain chemicals, such as formaldehyde, may have precipitated allergic reactions in the atopic workers. The sensitized employees should minimize exposures to any chemicals that might trigger attacks. Use of protective clothing, improved housekeeping practices, and annual medical examinations are recommended.
NIOSH-Author; HHE-79-86-675; Region-1; NIOSH-Health-Hazard-Evaluation; Colleges; Hazards-Unconfirmed; Aldehydes; Medical-personnel; Work-practices; Work-environment; Air-contaminants; Allergic-reactions; Sensitization; Medical-screening; Control-measures; Author Keywords: angioneurotic edema; laboratory; formaldehyde
Field Studies; Health Hazard Evaluation
NTIS Accession No.
National Institute for Occupational Safety and Health
Page last reviewed: September 2, 2020
Content source: National Institute for Occupational Safety and Health Education and Information Division