Information contained in the U.S. Beryllium Case Registry is reviewed, including new information that was added between 1973 and 1977. The registry contains information on the epidemiology, diagnosis, clinical features, course, and complications of beryllium (7440417) related diseases. Between 1973 and 1977, 55 cases of beryllium disease have been added to the Registry files, to bring the current total of registered cases to 887. Of these 887 cases, 631 have been classified as chronic, 212 as acute, and 44 as acute cases in which chronic beryllium disease developed subsequently. Of the 55 cases admitted between 1973 and 1977, 40 were males, and 15 were females; fifty one of these cases were related to industrial or occupational exposure. The authors conclude that data from the registry support the fact that chronic beryllium disease is a continual occupational hazard.