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Histopathologic classification of bronchogenic carcinomas among a cohort of workers occupationally exposed to beryllium.
Environ Res 1980 Feb; 21(1):10-14
Pathology reports and specimens of 27 respiratory cancer victims were examined. The subjects had been occupationally exposed to beryllium (7440417) for an undetermined length of time. Microscope slides of tumor specimens were reviewed, tumor histology was classified, and smoking histories were determined from clinical records. In 25 of the cases, the primary site of malignancy was the lung: five of these malignancies were epidermoid carcinomas; nine were small cell anaplastic carcinomas; six were adenocarcinoma, bronchogenic type; two were adenocarcinoma, bronchiolar alveolar type; and three were large cell undifferentiated carcinomas. Among the 25 lung cancer patients, 17 were smokers at the time of hospitalization or were former smokers. The authors conclude that their evidence is insufficient to define the types of specific tumors associated with beryllium exposure.
NIOSH-Author; Respiratory-system-disorders; Carcinogenesis; Mortality-data; Statistical-analysis; Metallic-poisons; Air-contamination
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Page last reviewed: April 12, 2019
Content source: National Institute for Occupational Safety and Health Education and Information Division