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HHE determination report no. HHE-78-31-623, Olin Corporation, Ashtabula, Ohio 44004.
Cincinnati, OH: U.S. Department of Health, Education, and Welfare, Public Health Service, Centers for Disease Control, National Institute for Occupational Safety and Health, HHE 78-31-623, 1979 Oct; :1-7
Medical evaluations of 15 workers were made at the Olin Corporation (SIC-2899) in Ashtabula, Ohio on April 27 and 28, 1978 to determine the health effects of exposure to toluene-diisocyanate (26471625) (TDI), phosgene (75445), and toluene 2-4 diamine (95807) (TDA). A representative of the Oil Chemical and Atomic Workers Union, Local 7- 629, requested the evaluation on behalf of 57 members, some of whom were suffering from hyperactivity, nervousness, and irritability. Thirteen of 15 workers reported upper respiratory tract symptoms, 7 reported symptoms of chronic bronchitis, 7 reported chest tightness and wheezing associated with work, and 4 of 14 had one or more abnormal pulmonary function test results. The authors conclude that the rate of reported respiratory signs and symptoms was higher than expected among the 15 workers, but some symptoms may be related to stress. The 15 workers may not be a representative sample of the 57 employees. The following steps are recommended: the entire factory population should be surveyed periodically for symptoms of lower respiratory tract disease and lung function abnormalities that may be caused by chemical exposure; TDI exposure should be ended for sensitized workers or for those with excessive decline in lung function; and liver function and genetic damage evaluations should be performed periodically on TDA exposed workers.
NIOSH-Author; HHE-78-31-623; Unions; NIOSH-Health-Hazard-Evaluation; Region-5; Hazards-Unconfirmed; Chemical-industry; Chemical-factory-workers; Medical-evaluations; Chemical-exposure; Respiratory-function-tests; Respiratory-system-disorders; Biological-monitoring; Physiological-response; Physiological-testing; Author Keywords: toluene diisocyanate; phosgene; toluene 2-4 diamine; respiratory symptoms; lung function test
26471-62-5; 75-44-5; 95-80-7
Field Studies; Health Hazard Evaluation
NTIS Accession No.
National Institute for Occupational Safety and Health
Page last reviewed: March 11, 2019
Content source: National Institute for Occupational Safety and Health Education and Information Division