Radiation, Smoking and Height Relationships to Lung Cancer in Uranium Miners.
Archer-VE; Gillam-JD; James-LA
Proceedings of the Third International Symposium on Detection of Cancer, April 26-30, 1976, New York 1978:1689-1712
A prospective mortality study of 3366 white underground uranium (7440611) miners with 1 month or more underground employment before January 1, 1974, and 1231 surface workers with 1 month or less underground uranium mine employment, was conducted through September 1974 to determine radiation, smoking, and weight relationships to lung cancer. Radiation exposure responses varied with worker height, cigarette smoking and latent period. Radiation was more important than height, free silica (7631869) or cigarette smoking. Underground worker respiratory cancer rates were 4.9 times greater than expected from general population data, and 6.0 times greater than surface worker rate. Underground worker bronchogenic cancer rate was 6.5 times higher than amount the general population and among controls. Underground worker death rate from other respiratory diseases was 5.0 times greater than the general population and 1.7 times greater than the control. Underground workers had a much higher work related accidental death rate than did the general population or controls. Cigarette smokers had more benign and malignant lung disease than nonsmokers. Small miners had more lung disease than large miners. Results suggest that short miners receive higher noxious agent dosage than tall miners per lung tissue unit when doing equal work. It was concluded that airborne noxious agents' standards should consider amount of physical labor involved, and individual workers' sizes.
Mining-industry; Radiation-hazards; Pulmonary-system-disorders; Mortality-rates; Physiology;
Asthma and Chronic Obstructive Pulmonary Disease; Disease and Injury; Pulmonary-system-disorders;
Proceedings of the Third International Symposium on Detection of Cancer, April 26-30, 1976, New York