NIOSH Backup Data Report Pentachlorophenol S297 (Set 4).
NIOSH 1977 Dec:20 pages
A protocol for validation of the method for collecting pentachlorophenol (87865) was tested. For validation, the absolute total error (Sampling and analysis of air monitoring) should be less than 25 percent in at least 95 percent of the samples analyzed at the level of the OSHA standard. Validation consisted of development of a high performance liquid chromatographic (HPLC) method for the analysis of pentachlorophenol; analysis of a total of 18 analytical samples prepared by adding pentachlorophenol, 99 percent to 37mm Type-AA-Millipore filters, 0.8 micrometer pore size; analysis of a set of 18 samples collected from dynamically generated test atmospheres of Dowicide EC-7; determining the collection efficiency on mixed cellulose ester membrane filters, connected in series to a backup bubbler; testing of the storage stability of six collected samples; and assessment of precision and accuracy. The HPLC method passed all program requirements.
NIOSH-Author; NIOSH-Analytical-Method; Standards-Completion-Program; SCP; Standards; Sampling; Set-4; Backup-data; Phenols; Analytical-Method; Carbinols; Instrumentation; Air; Air-contaminants;
Division of Physical Sciences and Engineering, NIOSH, Cincinnati, Ohio, 20 pages, 4 references