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Health hazard evaluation determination report: HHE-77-103-474, Occidental Chemical Company, Lathrop, California.

Authors
Whorton D; Melby TH; Stubbs HA; Meyer CR; Wilcox T
Source
Cincinnati, OH: U.S. Department of Health, Education, and Welfare, Public Health Service, Centers for Disease Control, National Institute for Occupational Safety and Health, HHE 77-103-474, 1978 Mar; :1-94
NIOSHTIC No.
00080153
Abstract
Workers involved in the manufacture of agricultural chemicals at Occidental Chemical Co. (SIC-2879) were evaluated for possible exposure to hazardous amounts of toxins. Two groups of workers were compared for age, time worked in agricultural chemical manufacture, serum testosterone, follicle stimulating hormone and luteinizing hormone. Also semen analyses were conducted. Employees in the evaluated area at the time of the study were judged to be exposed to toxic concentrations of dibromochloropropane (96128) (DBCP). Workers who had an occupational history that included exposure to DBCP were more likely to have abnormalities of sperm counts than controls. Testicular biopsies done in ten individuals as well as cumulative DBCP exposure history indicate a dose response type of situation. Those workers who were exposed the longest were more likely to have reduced or zero sperm counts.
Keywords
NIOSH-Author; NIOSH-Health-Hazard-Evaluation; HHE-77-103-474; Hazards-Confirmed; Region-9; Air-sampling; Agricultural-chemicals; Air-quality-measurement; Air-contamination; Brominated-hydrocarbons; Chlorinated-hydrocarbons; Insecticides; Pesticides; Hormones; Blood-sampling; Serology; Industrial-hygiene; Chemical-manufacturing-industry; Occupational-health; Author Keywords: Dibromochloropropane; DBCP; Sperm Count Abnormalities
CAS No.
96-12-8
Publication Date
19780301
Document Type
Field Studies; Health Hazard Evaluation
Fiscal Year
1978
NTIS Accession No.
PB82-197443
NTIS Price
A06
Identifying No.
HHE-77-103-474
NIOSH Division
DSHEFS
SIC Code
2879
Source Name
National Institute for Occupational Safety and Health
State
CA; OH
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