NIOSHTIC-2 Publications Search
Organomercurials. Occupational hazards.
Authors
Anonymous
Source
NIOSH 1977 Oct; :227-296
NIOSHTIC No.
00075434
Abstract
The molecular structure, chemical abstracts service number, registry of toxic effects of chemical substances number, production figures, uses, and producer and user data, are provided for phenylmercuric- acetate (62384), phenylmercury-propionate (103275) and ethyl-mercury- chloride (107277). These mercury (7439976) compounds cause skin necrosis in animals after acutely toxic subcutaneous injections. Nerve tissue damage is the major pathologic feature of exposure to alkyl-mercury-compounds. Chronic effects include carcinogenicity, mutagenicity, and teratogenicity in animals. In human beings, all mercury compounds cause shock, cardiovascular collapse, and acute renal failure, skin damage including erythema, intense itching, edema, papules, pustules, and deep ulcerations, motor incoordination, concentric constriction of visual fields, hearing loss, emotional disturbances, and mental impairment. A list of organomercurial medicinals and pharmaceuticals is given, and also threshold limit values for organomercurials.
Keywords
Contract-210-77-0120; NIOSH-Contract; Organo-mercury-compounds; Heavy-metals; Nervous-system-disorders; Neuromotor-disorders; Mutagens; Carcinogens; Teratogens; Genetic-disorders; Skin-disorders; Exposure-limits; NIOSH-Publication
CAS No.
62-38-4; 103-27-5; 107-27-7; 7439-97-6
Publication Date
19771001
Funding Type
Contract
Fiscal Year
1978
Identifying No.
Contract-210-77-0120
Source Name
Information Profiles on Potential Occupational Hazards, NIOSH Contract No. 210-77-0120, October 1977
Page last reviewed: May 5, 2020
Content source:
National Institute for Occupational Safety and Health
Education and Information Division