NIOSHTIC-2 Publications Search

Organomercurials. Occupational Hazards.

Anonymous

NIOSH 1977 Oct; :227-296

http://www.dtic.mil/dtic/tr/fulltext/u2/a329029.pdf

00075434

The molecular structure, chemical abstracts service number, registry of toxic effects of chemical substances number, production figures, uses, and producer and user data, are provided for phenylmercuric- acetate (62384), phenylmercury-propionate (103275) and ethyl-mercury- chloride (107277). These mercury (7439976) compounds cause skin necrosis in animals after acutely toxic subcutaneous injections. Nerve tissue damage is the major pathologic feature of exposure to alkyl-mercury-compounds. Chronic effects include carcinogenicity, mutagenicity, and teratogenicity in animals. In human beings, all mercury compounds cause shock, cardiovascular collapse, and acute renal failure, skin damage including erythema, intense itching, edema, papules, pustules, and deep ulcerations, motor incoordination, concentric constriction of visual fields, hearing loss, emotional disturbances, and mental impairment. A list of organomercurial medicinals and pharmaceuticals is given, and also threshold limit values for organomercurials.

Contract-210-77-0120; NIOSH-Contract; Organo-mercury-compounds; Heavy-metals; Nervous-system-disorders; Neuromotor-disorders; Mutagens; Carcinogens; Teratogens; Genetic-disorders; Skin-disorders; Exposure-limits; NIOSH-Publication

62-38-4; 103-27-5; 107-27-7; 7439-97-6

19771001

Contract

1978

Contract-210-77-0120

Information Profiles on Potential Occupational Hazards, NIOSH Contract No. 210-77-0120, October 1977