NIOSHTIC-2 Publications Search
Vinyl Cyclohexene Dioxide Occupational Hazards.
NIOSH 1977 Oct; :54-57
This information profile on vinyl-cyclohexene-dioxide (4223103) lists its molecular structure, Chemical Abstracts Service number, Registry of Toxic Effects of Chemical Substances number, production figures and economic trends in production, use, number of companies producing and using the substance, and the biological effects of exposure. Acute and chronic effects of exposure are discussed. Vinyl-cyclohexene-dioxide is irritating to the eyes and skin of rabbits. It can cause acute respiratory tract irritation and congestion of the lungs. It has been associated with testicular atrophy, leukopenia, and necrosis of the thymus. Several studies have demonstrated the carcinogenicity of vinyl-cyclohexene-dioxide in rodents. Vinyl-cyclohexene-dioxide also inhibits the growth of Walker cell carcinoma in rats. No studies have been encountered on the effects of this compound on humans. There is no threshold limit value nor are there other exposure standards.
NIOSH-Contract; Contract-210-77-0120; Resins; Carcinogens; Coatings; Blood-disorders; Chemical-processing-industry; Adhesives; Epoxy-resins; Synthetic-resins; Pathology; Irritants; Respiratory-system-disorders; Eye-irritants; Skin-irritants;
Asthma and Chronic Obstructive Pulmonary Disease; Disease and Injury; Respiratory-system-disorders;
Information Profiles on Potential Occupational Hazards, NIOSH Contract No. 210-77-0120, October 1977
Page last reviewed: January 14, 2022
Content source: National Institute for Occupational Safety and Health Education and Information Division